1,284 Analyzed Papers
42,910 FDA Side-Effect Signals
148 Active Global Trials
— Trials Recruiting Now

Annual Research & Trial Trends

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Research Share by MoA Target

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Live Drug Repurposing Candidates

How FollicleIQ Works (3-Step Guide)

Accelerate your hair science R&D in three simple steps—from query to corporate B2B export.

01

Search Targets & Molecules

Enter any target protein, gene symbol (e.g. AR, SRD5A2), or chemical molecule name (e.g. Minoxidil, Finasteride) into our AI engine.

02

Synthesize NIH & FDA Metrics

Review real-time aggregated signal metrics: PubMed clinical literature count, OpenFDA FAERS adverse effect ratios, and ClinicalTrials.gov progress.

03

Export B2B PDF & Excel Reports

Instantly generate and download fully cited, audit-ready PDF briefs and Excel (.xlsx) spreadsheets for corporate executive and lab presentations.

Frequently Asked Questions (FAQ)

Everything you need to know about FollicleIQ data sources, subscriptions, and security.

Where does FollicleIQ source its biomedical data?

FollicleIQ directly queries official public REST APIs provided by the U.S. National Institutes of Health (NIH PubMed), U.S. Food & Drug Administration (OpenFDA FAERS), ClinicalTrials.gov, EMBL-EBI ChEMBL, UniProt, and AlphaFold Protein Structure Database. All analytical metrics include verifiable direct PMID and NCT reference links.

How does the monthly PayPal subscription work?

After selecting your preferred tier (Researcher Pro at $49/mo or Corporate Enterprise at $299/mo), you authorize a 1-click PayPal Subscription. PayPal handles automatic monthly billing securely. You can manage or cancel your subscription at any time directly via your PayPal account dashboard or by contacting our support team.

What is your refund policy?

We offer a 7-Day 100% Risk-Free Refund Guarantee. If FollicleIQ does not meet your research or corporate data needs within 7 days of subscribing, simply request a full refund, no questions asked.

Can I export reports for corporate presentations?

Yes! Researcher Pro and Corporate Enterprise subscribers enjoy full export rights to formatted PDF executive summaries and raw Excel (.xlsx) dataset tables for inclusion in pitch decks, grant proposals, and internal corporate R&D briefs.

PubMed & BioRxiv Hair Loss Fact Analysis

AI collects research papers and provides 3-line fact summaries, targets, and key molecules.

FDA Adverse Event (FAERS) & Signal Analysis

Tracks hypertrichosis (hair growth) side-effect signals for drug repurposing.

Top Hypertrichosis Report Drugs (Repurposing Candidates)

Generic Name Original Indication Hypertrichosis Cases Repurposing Potential Fact Analysis

FDA Side-Effect Signal Comparison

Global Clinical Trials Pipeline

Tracking 148 active global clinical trials on Alopecia (ClinicalTrials.gov).

NCT ID Trial Title Sponsor / Pharma Phase Target / Therapy Status

Target Protein & Compound 3D Explorer

Integrated public facts from ChEMBL, UniProt, and AlphaFold 3D structure predictions.

AlphaFold & ChEMBL 3D Protein-Molecule Simulation

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Mean pLDDT (model confidence) —
ChEMBL target —
Very high >90 Confident 70–90 Low 50–70 Very low <50
AR (Androgen Receptor)
Inhibitor Required
Androgen Receptor (5α-reductase Follicular Atrophy)
💡 Biological Fact: Binds DHT to induce TGF-β1 in dermal papilla cells. Inhibition extends follicle lifespan.
Skin Permeability (LogP): 3.2 (Excellent Absorption, 372Da)
Patent Freedom (FTO): Patent Expired (Free FTO)
IC50 Potency: Finasteride (12.4 nM) / Dutasteride (0.5 nM)
GSK-3β / Wnt Path
Activator Required
Glycogen Synthase Kinase 3β (Stem Cell Regen)
💡 Biological Fact: Blocking GSK-3β accumulates β-catenin to trigger Telogen to Anagen transition.
Skin Permeability (LogP): 2.8 (Topical Formulation Fits)
Patent Freedom (FTO): New Use Patent Filing Area
IC50 Potency: Valproate Deriv (8.2 nM) / CHIR-99021 (9.8 nM)
CRTH2 (PTGDR2)
Inhibitor Required
Prostaglandin D2 Receptor 2 (Inflammatory Atrophy)
💡 Biological Fact: PGD2 is 3x higher in balding scalp. Blocking CRTH2 prevents follicle miniaturization.
Skin Permeability (LogP): 3.9 (Lipophilic Scalp Lotion Fit)
Patent Freedom (FTO): Repurposing Opportunity Available
IC50 Potency: Ramatroban (24.1 nM) / Setipiprant (67.0 nM)

Real-Time Fact Alert Engine

Automated AI notifications triggered on new PubMed papers, FDA signals, or ClinicalTrials.

Register New Fact Alert Keyword

Active Subscription Alert Feeds

Keyword Target DB Channel Latest Captured Fact Status
Wnt/β-catenin PubMed, ClinicalTrials Email (Daily) PMID: 38912041 New Paper Captured Active Monitoring
JAK3 Inhibitor OpenFDA, ClinicalTrials Slack Webhook Pfizer Phase 3 Status Updated Active Monitoring

FollicleIQ SaaS Subscription Tiers

100% Fact Automation Solutions for Researchers, Cosmetic R&D, and Beauty Enterprises

Free Fact Trial

Starter Fact

$0 / mo

Basic alopecia papers & FDA side-effect fact search trial

  • PubMed Basic Search (50/mo)
  • OpenFDA Major Side-Effects
  • No Real-Time Alerts
  • No PDF/Excel Export

Researcher Pro

$49 / mo

Tailored plan for bio researchers and dermatologists

  • Unlimited 360° Fact Search
  • AlphaFold 3D Explorer & Real-Time Alerts
  • 10 PDF B2B Report Exports / mo
  • 100% PMID/NCT Direct Fact Links
Enterprise B2B Tier

Corporate Enterprise

$299 / mo

For Pharma, Biotech, and Cosmeceutical R&D Teams

  • Multi-User Shared Workspace
  • Unlimited Real-Time Alerts (Slack/Email)
  • Unlimited PDF & Excel Raw Data Export
  • Drug Repurposing Full Access

Automated B2B Fact Report Generator

Generate verified fact briefing reports based on public database evidence for cosmetic R&D and labs.

Custom B2B Report Settings

Report Live Preview (Fact Summary Sample)